Description:
Bovine, skin. There are disseminated cutaneous papules.

Description:
Bovine, skin. There are disseminated cutaneous papules with necrotic centers (sitfasts).

Description:
Bovine, skin. Necrotic centers (sitfasts) of two of these papules have sloughed.

Description:
Bovine, skin. Removal of the necrotic center (sitfast) of a papule.

Description:
Bovine, skin. There is hemorrhagic exudate subjacent to the necrotic center (sitfast) of a papule.

Description:
Bovine, skin. Multiple subcutaneous nodules elevate the skin.

Description:
Bovine, muzzle. There are multiple sharply-demarcated slightly raised papules, often with eroded surfaces, that extend into the nares.

Description:
Bovine, nasal turbinate. Early pox lesions are slightly pale round foci rimmed by petechiae.

Description:
Bovine, nasal turbinate. The centers of well-developed pox are necrotic.

Description:
Bovine, nasal turbinate. Nasal mucosa contains several macules with hyperemic margins.

Description:
Bovine, trachea. The mucosa contains a poorly demarcated round focus rimmed by mild hemorrhage (early pox lesion).

Description:
Bovine, trachea. Two coalescing mucosal macules have hyperemic margins.

Description:
Bovine, lung. There is marked generalized interlobular edema, and there is a small cluster of red nodules on the left side of the specimen.